Since the 1960's he has been working for several architecture offices, such as J.C Louring, Frederiksberg, Kalundborg, Henry & Niels Kryger and Holte Design Studios in Denmark.
In 1969 he created the light "Norm69" for the company Normann Copenhagen and got his inspiration from the nature. In 2002 "Norm69" awarded the Formland-Prize and received the title "Best Item" at the IMM in Cologne.
The past 10 years Karkov mainly worked for the Municipality of Frederiksberg. During this period he left his mark on several projects as for example Frederiksberg Hospital and Frederiksberg Gymnasium.
Today Simon Karkov is enjoying his retirement in Turkey working on smaller projects.